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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed21809493cb84f78094437505d2de781120e432ab057e837ca09c72e087502' 
  AND token = 'Z9d4ZUBALjxLrqpJaVPvlLGECFP3oIuV0YbGcaIBrpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}