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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249dfb6c397b2b9c23825631a1ff52f1249b464ba594c563ab6545058f82af63' 
  AND token = 'BCH6bWUP+7s3MVN1tsG0dBrXr9vwWiHXlltANUE2L5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}