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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4c99c52fdce24ed02233136a5c6d19d0302dbe8052390f53924f27852e6d27e' 
  AND token = 'nJLCucCxMexHyGmk3eGDt8cpLlcRygirSstMzN9XXCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}