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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3aad0c3878a9e97280cd520abf46c357854282ee22a8da014187aac9bfe7681' 
  AND token = 'aRUREkZrU/fdJoPvyanM9aR+GD2at7Xh0QDDdhmoF9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}