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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6de03beb5cda70051c0a3108a07886c055a9073f87f2422e9f46d51f2993cfcd' 
  AND token = 'pVU1AJ8RSoKSoWY6+DB0qlcTXwimdGyVU1MN3vfXHfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}