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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'defe611c6b5d2c13b1ce4d95509551154faa127b4381c467cd37e7dfe2364ff5' 
  AND token = 'Gm4xep9++j8JtofsYMkgT/H4xXx51p0olKKwe+h8s/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}