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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a665dfce11541b43fc873b73b4008d42409c43fe5d5b51df36d3ec187649ad' 
  AND token = 'POLTD0QIyuzDg2xXCgEnMaovHiEVzO5bzTekh2y7HGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}