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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92cd3949fbcd58e27e316b43aea3d47a91cbf07e185f5c0f3efe85444f817591' 
  AND token = 'wWfmkHOQfIkAym9uQ7GUwoyItCPdLMLwLQDPIP8mw4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}