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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '360eeb410268ca3c063afba73dde7b806ad35703e456aca53216a5f0d1062212' 
  AND token = 'ybpv8aAuvu3UodSa6LjY7zonA81Uwc78KRCAOZFaHts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}