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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fbd942d6c2aa461c0f1a722c4dd94fa66fd6d880894de600f9997c9a6dd8016' 
  AND token = 'R0aIf5PdXLYGwJu4y44QJydEtRmmBxKXsqKq/Zna+uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}