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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05380dd0226bcc55e3e45ae26ecfab95145aa8e8a2a5a19e44840f8ccd41d1d1' 
  AND token = 'LYFDt2ELYh8Vn+RslG996sNfysUYq0stlc7SAp49gDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}