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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9878227ff9b62fdb482ff9a1c0bcae31e1fa4a2f026afa514790b369ca77b701' 
  AND token = 'QpM5B2rOGYLRntXrlyG4FsWCFGjJCfu+34OEN45XTmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}