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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dbb71dc4b4b6a455cc0c6da81a94b0a65d60a48272b30da7b7f30c96e61647d' 
  AND token = '5PuNEf4I+b1ZbNMpWKsf/62ek77AGSTwAf3gfTJEE4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}