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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e40f3a1057a471b104d432ed2e3d37148c612aca4afb103c24a4a92e3016af' 
  AND token = 'mRXbYVWssCcYKEaIKGYsflUOTTDGSrAQJTCnXCoy0Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}