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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59fc3009a16c0f2aeb2fe16a744ea2e2eb646317251846f8054cbf0b9ba0b0c8' 
  AND token = 'r1xSZSf27RvPq5CIAT5+eP/6DcPlV9jGNybQ2PcExLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}