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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac04a6101fab218b2805dc9c4569e3a0aa47c8b4138daa97bf889e72fa41328' 
  AND token = 'gdtsT2M2pwGbuSdGYKUtZqfSxZIXfJThizkqTakKweM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}