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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91450a52ddcc79f35a3717798357c66015084e0ffdf7a159dcab5f35dfce3170' 
  AND token = '65bfFhempslR8H2DSmfJWD2gb2wA7B3PbFyesktTy10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}