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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb446a4419875d9e800e29c9f9f4fd9f4ddb59a04ca0c0cb3ad59267fc75a08' 
  AND token = '8KxVG8yjcgebBnHXOj6PZNGYxiijW/sM68wyffPYeFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}