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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5ee3b5a7b45fa42947aee2cfd687abad7d2d3d66867c215aa3c1dcde2378c35' 
  AND token = 'pBVEB0GMzHz1nPWkVV8/glzVQ1OrSAo7IYhmOlpFwX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}