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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd0e5eed9ee7deef5b5370becf89e137f17d75e51589572ec6f171c8604dead' 
  AND token = '9I5R3QN7Rkj0omCLXEieIUgvcY3zm1lsziP0B321EtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}