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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1798c191064c3dd87abacf453677cc8d0f9bb3728d2486bd46e2c270de3ffeb' 
  AND token = 'QJCdr4CaUiIL1waFQ9Xz4ZWZ0t21fDiYfuBx7AkHmyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}