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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741e8bbeced9b8a63dc3fe60ec4f501e64bfb5753eb0093a54af516811dba5c5' 
  AND token = 'z4HFgKBDjCLfuZXHVuc7dCkukGsUDfI7cOEsL0RLUp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}