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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d11bb305c0fd506c31c410976dd14abb77f0f0f5239e20dfb9c10c38d4d8df3' 
  AND token = 'if9HPsrwSP/VxzZuy4fX+CaCKiRASf80Yf3ZbEPDJOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}