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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b103a53f2a46b2d1381f17929873c4af85f02110baf630d47a968ed5cc1b46' 
  AND token = 'TSEXEZFhFdX1FcetJuiChEQYbhanbLAKbgvT2c8y7d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}