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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '149c8f8db2cd68683ac8c8bea3509612da8c7539b1ce68c6e006d129ed1d2f5a' 
  AND token = 'JN0z4TIHf85mWRHyPIFqNQb1tpxuGJFsTQp24XxpUGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}