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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c9c130864f2dda068e6839d00e4c0bfda0bd3f948651d87b6c560a242323b2d' 
  AND token = 'eTqXR93AKoYynTcu0JzXggS0ERFBFApwJ02z9ZW9Bls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}