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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d921d374d633eb721e1093f40cedd43c659eb5dfe7d5e296837a2aaac2a67e' 
  AND token = '0tXp6W5fX0/FfztfzIXECee9EU/oBWk8S4ylzCw+vyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}