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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd34e8419729bed0a18554553e66703f278f58fd0a3bb4065da067295b87be445' 
  AND token = 'DxAbNWShrOMgjunNRzziFIS71n2Z5INTtdn2Z9a/cpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}