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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9e85cd1ff309c00d2245f891d85697a4461fa9cd1434d6daaff3313ee0fe402' 
  AND token = 'VcLMzuAlRttTTpaMCzNMRi+ZbqoIK/DZ06W32YHk+2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}