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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '377da108b2518c0fa45aaba3be7a3c9c7e062e357dc94c5a0df74a12567b1894' 
  AND token = 'Rsi6MP7x7aIRNB9uHfhknu65QP9kRSuDtA1+MUXK1qg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}