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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e75d524b3c45f023f3b480049f9fcc751b773e6ca4c4b453be304078e0f8775d' 
  AND token = 'Z1KyxNrbBxFTZRaJYGOEXEM4hyyMxSABTP4CFR6LTAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}