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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfb4c1d8ad0e935116c81683cd307d70e7c0145732dcce2b4247171e068f1949' 
  AND token = 'JOR+9eNbS3/E3s0lbKaUCBO3bdIy8XBpnStNRBRN7l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}