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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af3a71c54bbc034de17dd5c2b5878ae4e9363f64739a525fedc8c6709b0e9ac' 
  AND token = 'DSaNORw21RYA8qOnMJrDkdmdmnC1VCTTDL4+Iyq3fxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}