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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce5286e2b49de956d94c854a47cdffddbc87fe92e51595cf162dc3490eeab435' 
  AND token = 'KdaWqPisQQApungM/vBoio5KB5+bakxn78wsT03FNPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}