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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0170228bd4dd67862c06d38804d5b4bfc3c652d32b12a40381a93bc120720b9f' 
  AND token = 'iNhlyPa8Da0bdPCTxdOik/ZYiRfn4C6Ajw7mEaMq/A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}