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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a01e12f51ecf158c2daf71800933d5ab27c1dde97f9f8bb227b2811a073ecaf' 
  AND token = 'PYiAyDYvl5M+G6KH3xIDX+Yy6Dwy1ShHqiWniZB4/yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}