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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b1ceac615067939beae717664dab30bc75214651c2beb09b82fba927fb2dc4a' 
  AND token = '/JUW21UmsIau2wU+tEF+AgJzm5zaml9Nwl+2uQ4RFZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}