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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04cb3c0bf43e417472de2f4eaf4aa1b4d42f3bc6e30d73d05f8649585c137c11' 
  AND token = 'JJ3050xiK51N6eXx6pJfuawZp3FKAXAzllm85OqB8uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}