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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8072a16f022a2c8128f77f4c5dba200cab1fc860eb2656c0b3f49ebb840156' 
  AND token = 'R0YmfPImz1MrDgA/vU59ztoy4wPG+Fqo9xYh8N5JAFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}