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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d7d52e6a2e86bb051226127cb5e085967c6873e3c8f2a2e4501d530c46bf027' 
  AND token = '4lms/nv24U7lQ4fBOTXt4Pr/ANacSCf+Ifn2Bsu6MjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}