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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e00b40e50ec25b2077ab6783fc74c7c990c6160424c67578594280bd7335071' 
  AND token = 'a6Q0Hwj9wK04eMAsY3FGGudntYCHoTWjm5HQqGZqd38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}