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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755195256ed765dd6728eac900be92865c6f2c1b5e22402a43ff6fa50621375b' 
  AND token = '4b8zZZmehB5HcxkJmm9WgNaDt4k1+GNl34SivW0SnAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}