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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'add521902bd1277dc22aa2be80bf47cb279b897c2dec0637eb17035625d2a0a0' 
  AND token = 'fRBEeTbhf7xzaj8qizw6YmAYHKs51VUZwF8bzTvfsNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}