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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9dc746f2a7d7400ff9ff80762de0fc08147455a1de490b9833006b5d945eac' 
  AND token = '25EpJP35wpNiuCi6oYMko60xDDwVjKa024RE+9srifU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}