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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f10b741b1cf6a98c9559cd2e2694ea01143efdcf3ad4ea2ac4863c13535606ad' 
  AND token = 'upH0qb1Y+a/zCf/chx99QIPhcN8mtK1JdNnt9rTM11I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}