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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cd9634a92f3d4a9552e2e8e5f3afee6b378f74bc9fb67f30da8ff4514816bbc' 
  AND token = 'pIyDt8xH03O5WfG2CsnlwtN9vCqFnrcx8YF5guJUbXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}