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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b41fb06d90838f9ba87fc734a2cf4b75c4c87fef2439ef19de15e9fa7a659fe' 
  AND token = 'AQbW9EftWdp5nnJwrabv0zJXc/72K+WvKCOk/+LCmpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}