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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb202a7e490a899a2b29c05e7b1529e8043a3249dcfd52faa61bb91d0b32285' 
  AND token = '0k/TqZBQhT9YqqmLL5/xEyz4oA7m6FAKavHvDN9i27I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}