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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49dea446f6e74aa8b2c7dcba4c1010594e3cfdc2868faf0114bcdec06bf6828c' 
  AND token = 'qRbI3CD3kNB5LCzgS6oRkFipeYodfj2WQj6XAGH4fRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}