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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e4319da81038324d6a63631fee0b80d96e425b8eb52b6e253fe5ba771783ee1' 
  AND token = 'Ph23qS+2Zw3n5TZS7dHDZznhNfHxKjNKthveuE8pcAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}